Effect of prolonged dietary administration of vanadate on blood pressure in the rat.

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Effect of prolonged dietary administration of vanadate on blood pressure in the rat.

Vanadate, a potent naturally occurring Na+,K+-ATPase inhibitor thought to have a role in regulating Na+-K+ pump activity, was fed to uninephrectomized rats drinking tap water or a 1% solution of sodium chloride for as long as 56 weeks. Feeding was achieved by adding sodium orthovanadate to normal rat chow equivalent to 100 or 200 ppm vanadium by weight. In the rats drinking tap water, systolic ...

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ژورنال

عنوان ژورنال: Hypertension

سال: 1981

ISSN: 0194-911X,1524-4563

DOI: 10.1161/01.hyp.3.3_pt_2.i173